Hormonal Regulation of Testis MCQ Questions and Answers
1. Which hormone from the hypothalamus stimulates the pituitary gland to release LH and FSH in males?
A. Gonadotropin-releasing hormone
B. Testosterone
C. Inhibin
D. Growth hormone
Correct Answer:
Gonadotropin-releasing hormone
Explanation:
Gonadotropin-releasing hormone, or GnRH, is secreted by the hypothalamus and stimulates the anterior pituitary to release LH and FSH.
2. Which pituitary hormone acts on Leydig cells in the testes?
A. Follicle-stimulating hormone
B. Luteinizing hormone
C. Thyroid-stimulating hormone
D. Prolactin
Correct Answer:
Luteinizing hormone
Explanation:
Luteinizing hormone, or LH, stimulates Leydig cells to produce and secrete testosterone.
3. What is the main function of testosterone in the hormonal regulation of the testes?
A. It stimulates the production of thyroid hormones
B. It supports male reproductive functions and spermatogenesis
C. It causes the release of insulin
D. It prevents the secretion of GnRH directly from the testes
Correct Answer:
It supports male reproductive functions and spermatogenesis
Explanation:
Testosterone produced by Leydig cells supports male reproductive functions and helps maintain spermatogenesis.
4. Which hormone primarily acts on Sertoli cells?
A. Follicle-stimulating hormone
B. Luteinizing hormone
C. Adrenocorticotropic hormone
D. Thyroid-stimulating hormone
Correct Answer:
Follicle-stimulating hormone
Explanation:
Follicle-stimulating hormone, or FSH, acts on Sertoli cells and supports their role in spermatogenesis.
5. Which hormone is secreted by Sertoli cells and helps regulate FSH secretion?
A. Inhibin
B. Testosterone
C. GnRH
D. LH
Correct Answer:
Inhibin
Explanation:
Sertoli cells secrete inhibin, which provides negative feedback mainly by reducing FSH secretion from the anterior pituitary.
6. Which hormone directly stimulates Leydig cells to secrete testosterone?
A. FSH
B. LH
C. Inhibin
D. GnRH
Correct Answer:
LH
Explanation:
LH binds to receptors on Leydig cells and stimulates them to produce testosterone.
7. High levels of testosterone generally reduce the secretion of which hypothalamic hormone?
A. GnRH
B. FSH
C. Inhibin
D. LH
Correct Answer:
GnRH
Explanation:
Testosterone participates in negative feedback and reduces GnRH secretion from the hypothalamus, helping regulate testicular hormone production.
8. Which sequence correctly describes hormonal control of testosterone production?
A. GnRH stimulates LH, and LH stimulates Leydig cells
B. LH stimulates GnRH, and GnRH stimulates Leydig cells
C. FSH stimulates LH, and LH stimulates Sertoli cells
D. Inhibin stimulates GnRH, and GnRH stimulates Leydig cells
Correct Answer:
GnRH stimulates LH, and LH stimulates Leydig cells
Explanation:
The hypothalamus releases GnRH, which stimulates pituitary LH release; LH then acts on Leydig cells to promote testosterone secretion.
9. What is the main hormonal role of FSH in the testes?
A. It stimulates Sertoli cells to support spermatogenesis
B. It stimulates Leydig cells to release testosterone
C. It inhibits the release of inhibin
D. It directly releases GnRH from the hypothalamus
Correct Answer:
It stimulates Sertoli cells to support spermatogenesis
Explanation:
FSH acts on Sertoli cells, which support developing sperm cells and contribute to the regulation of spermatogenesis.
10. Which combination correctly matches the hormone with its source and action?
A. LH—pituitary gland—stimulates Leydig cells
B. FSH—Leydig cells—stimulates testosterone release
C. Inhibin—hypothalamus—stimulates GnRH release
D. GnRH—Sertoli cells—stimulates inhibin release
Correct Answer:
LH—pituitary gland—stimulates Leydig cells
Explanation:
LH is released by the anterior pituitary and acts on Leydig cells to stimulate testosterone production.
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