1. What reaction is catalyzed by hexokinase during glycolysis?
A.
Glucose is converted into glucose-6-phosphate
B.
Glucose-6-phosphate is converted into fructose-6-phosphate
C.
Fructose-1,6-bisphosphate is split into two three-carbon molecules
D.
Pyruvate is converted into lactate
Correct Answer:
Glucose is converted into glucose-6-phosphate
Explanation:
Hexokinase catalyzes the phosphorylation of glucose to form glucose-6-phosphate in the first step of glycolysis.
2. Which molecule provides the phosphate group in the hexokinase reaction?
A.
ADP
B.
ATP
C.
NAD+
D.
Pyruvate
Correct Answer:
ATP
Explanation:
ATP donates its terminal phosphate group during the hexokinase reaction, forming glucose-6-phosphate and ADP.
3. What is the main product formed when hexokinase acts on glucose?
A.
Fructose-6-phosphate
B.
Glucose-6-phosphate
C.
Fructose-1,6-bisphosphate
D.
Pyruvate
Correct Answer:
Glucose-6-phosphate
Explanation:
Hexokinase adds a phosphate group to glucose, producing glucose-6-phosphate.
4. Which nucleotide is produced from ATP during the hexokinase reaction?
A.
AMP
B.
GTP
C.
ADP
D.
NADH
Correct Answer:
ADP
Explanation:
When ATP transfers a phosphate group to glucose, ATP is converted into ADP.
5. The hexokinase reaction occurs at which stage of glycolysis?
A.
First step
B.
Third step
C.
Sixth step
D.
Last step
Correct Answer:
First step
Explanation:
Hexokinase catalyzes the first reaction of glycolysis, in which glucose is phosphorylated to glucose-6-phosphate.
6. What type of chemical change does hexokinase perform on glucose?
A.
Oxidation
B.
Reduction
C.
Phosphorylation
D.
Hydrolysis
Correct Answer:
Phosphorylation
Explanation:
Phosphorylation is the addition of a phosphate group, and hexokinase phosphorylates glucose using ATP.
7. Where does the hexokinase reaction take place in a eukaryotic cell?
A.
Nucleus
B.
Cytoplasm
C.
Mitochondrial matrix
D.
Golgi apparatus
Correct Answer:
Cytoplasm
Explanation:
Hexokinase catalyzes the first step of glycolysis in the cytoplasm, where glucose is converted into glucose-6-phosphate.
8. Which equation correctly represents the hexokinase reaction?
A.
Glucose + ATP → Glucose-6-phosphate + ADP
B.
Glucose + ADP → Glucose-6-phosphate + ATP
C.
Glucose-6-phosphate + ATP → Glucose + ADP
D.
Pyruvate + ATP → Glucose + ADP
Correct Answer:
Glucose + ATP → Glucose-6-phosphate + ADP
Explanation:
Hexokinase transfers a phosphate group from ATP to glucose, producing glucose-6-phosphate and ADP.
9. How many ATP molecules are used in the hexokinase reaction per glucose molecule?
A.
None
B.
One
C.
Two
D.
Four
Correct Answer:
One
Explanation:
One ATP molecule is consumed when hexokinase phosphorylates one glucose molecule.
10. Which enzyme catalyzes the phosphorylation of glucose in the first step of glycolysis?
A.
Phosphofructokinase
B.
Pyruvate kinase
C.
Hexokinase
D.
Lactate dehydrogenase
Correct Answer:
Hexokinase
Explanation:
Hexokinase is the enzyme that transfers a phosphate group from ATP to glucose, forming glucose-6-phosphate.
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